Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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91
Tocris Bioscience™ Ambrisentan
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Selective ETA antagonist
92
Tocris Bioscience™ OGDA
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Green fluorescent D-amino acid; compatible with STED microscopy
93
Tocris Bioscience™ KYP 2047
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High affinity prolyl oligopeptidase inhibitor (Ki = 0.023 nM); anti-angiogenic, neuroprotective and brain penetrant
| CAS | 796874-99-2 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | (2S)-1-[[(2S)-1-(1-Oxo-4-phenylbutyl)-2-pyrrolidinyl]carbonyl]-2-pyrrolidinecarbonitrile |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C20H25N3O2 |
| Formula Weight | 339.44 |
94
| CAS | 19685-09-7 |
|---|---|
| Molecular Formula | C20H16N2O5 |
95
Tocris Bioscience™ Nicotinamide
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
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Nicotinamide synthesized to Ancillary Material Grade
96
| CAS | 256373-96-3 |
|---|---|
| Molecular Formula | C20H23N2NaO5S |
97
Tocris Bioscience™ FTBMT
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Potent and selective GPR52 agonist; orally bioavailable and BBB permeable
| CAS | 1358575-02-6 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 4-[3-[[3-Fluoro-5-(trifluoromethyl)phenyl]methyl]-5-methyl-1H-1,2,4-triazol-1-yl]-2-methylbenzamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C19H16F4N4O |
| Formula Weight | 392.35 |
98
R&D Systems™ Recombinant N/A Lewis X
Small and Specialty Supplier Partner
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Recombinant Protein
99
Tocris Bioscience™ MU 1742
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent and selective CK1α, CK1δ and CK1ε inhibitor
100
Tocris Bioscience™ tri-GalNAc COOH
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Asialoglycoprotein receptor ligand with PEG linker and carboxylic acid group for onward chemistry
101
Tocris Bioscience™ PAG 3'-piperazine-4-methylpiperidine
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Cereblon ligand with terminal piperidine for onward chemistry
102
Tocris Bioscience™ PAG 4'-piperazine
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Functionalized cereblon ligand for PROTAC development
103
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Thermo Scientific Chemicals Cyclobenzaprine hydrochloride
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Thermo Scientific Chemicals Cyclobenzaprine hydrochloride
CAS: 6202-23-9 Molecular Formula: C20H22ClN
| CAS | 6202-23-9 |
|---|---|
| Molecular Formula | C20H22ClN |
104
Tocris Bioscience™ JT010
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Potent and selective TRPA1 channel activator (EC50 = 65 nM)
| CAS | 917562-33-5 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 2-Chloro-N-[4-(4-methoxyphenyl)-2-thiazolyl]-N-(3-methoxypropyl)acetamide |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C16H19ClN2O3S |
| Formula Weight | 354.85 |
105
| CAS | 7770-78-7 |
|---|---|
| Molecular Formula | C21H24O6 |